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HPV vaccine can prevent 90 percent of genital warts in men

The human papilloma virus (HPV) infects the squamous epithelium, a layer of cells that line body surfaces, including blood vessels and body cavities. Infection is manifested by the growth of warts, which can progress to cancers in the genitals, anus and throat. HPV infection, including genital warts, is one of the leading sexually transmitted diseases worldwide.

A recent study found the HPV vaccine, used for girls to prevent cervical cancer, is effective in preventing anal and genital infection and development of external genital lesions (warts) in men. The vaccine is responsive to viral strains HPV-6, 11, 16 and 18.

The four-year clinical trial, published in The New England Journal Medicine, is an international analysis involving 4,065 males aged 16 to 26 years, coming from 71 sites in 18 countries. This is the first reported finding on HPV vaccine used as protection for men.

Results showed a nearly 66 percent effectiveness against lesions caused by the viral strains. About an 86 percent reduction in persistent infection with HPV-6, 11, 16 and 18 was observed. When offered prior to exposure of the viruses, the vaccine can prevent the development of genital warts by 90 percent.

Eighty-five percent of the respondents reported having exclusively female sexual partners while the rest reported having sex with male partners.

The Food and Drug Administration approved the vaccine in 2009 for wart prevention in men and expanded the approval the following year for anal cancer prevention.

“Vaccinating boys should help prevent HPV transmission to women, as well as transmission from men to men, and help reduce the incidence of the virus throughout the general population,” said epidemiologist Anna Giuliano, the lead author, from the H. Lee Moffitt Cancer Center and Research Institute, in Tampa, FL.

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Capital Surgeons Group is a group surgical practice specializing in bariatric surgery, breast surgery, colorectal surgery, laparoscopic surgery and robotic surgery at the following locations:

Central Austin

3705 Medical Parkway, Suite 250 and 210
Austin, TX 78705
Appointments: 512.302.1210
Office Hours: M-F, 8:00 am to 4:30 pm

North Austin/Round Rock

505 W. Louis Henna Blvd., Suite 220
Austin, TX 78728
Appointments: 512.498.4860
Office Hours: M-F, 8:00 am to 4:30 pm

South Austin

5625 Eiger Road, Suite 230
Austin, TX 78735
Appointments: 512.441.7755
Office Hours: M-F, 8:00 am to 4:30 pm